Ceritinib Dosage
Generic name: ceritinib
Brand name: Zykadia
Dosage forms: oral capsule (150 mg); oral tablet (150 mg)
Drug class: Multikinase inhibitors
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: CAP: 150 mg; TAB: 150 mg
Special Note
- [uses, dosing may vary]
- Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments
Non-small cell lung CA, metastatic
- [ALK-positive dz]
- Dose: 450 mg PO qd; Info: give w/ food
- [*ROS1-positive dz]
- Dose: 450 mg PO qd; Info: give w/ food
Renal dosing
- [see below]
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
Hepatic dosing
- [adjust dose amount]
- Child-Pugh Class C: decr. dose 33%
SRC: NLM .