Envarsus XR Dosage
Generic name: Tacrolimus Extended-Release Tablets
Drug class: Calcineurin inhibitors
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: ER TAB: 0.75 mg, 1 mg, 4 mg
Kidney transplant rejection prophylaxis
- [de novo transplant pts]
- Dose: 0.14 mg/kg/dose PO qam; Info: adjust dose based on serum levels; give on empty stomach; do not cut/crush/chew tab
- [pts converting from IR formulations]
- Dose: individualize dose PO qam; Start: approx. 80% of total daily IR tacrolimus dose; Info: adjust dose based on serum levels; give on empty stomach; do not cut/crush/chew tab
Renal dosing
- renal impairment: give lowest recommended dose, may consider further dose decr.
- HD/PD: not defined
Hepatic dosing
- moderate impairment: caution advised, monitor closely; Child-Pugh Score >10: decr. dose, amount not defined