Ixazomib Dosage

Generic name: ixazomib
Brand name: Ninlaro
Dosage form: oral capsule (2.3 mg; 3 mg; 4 mg)
Drug class: Proteasome inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  CAP: 2.3 mg, 3 mg, 4 mg

Multiple myeloma, relapsed or refractory

[4 mg PO x1 on days 1, 8, 15 of 28-day cycle]

Info: part of multi-drug chemo regimen; give at least 1h before or 2h after food; do not open cap

Renal dosing

[adjust dose amount]

CrCl <30: start 3 mg x1 on days 1, 8, 15 of 28-day cycle

HD: start 3 mg x1 on days 1, 8, 15 of 28-day cycle; no supplement after dialysis; PD: start 3 mg x1 on days 1, 8, 15 of 28-day cycle; no supplement

Hepatic dosing

[adjust dose amount]

bilirubin >1.5x ULN: start 3 mg x1 on days 1, 8, 15 of 28-day cycle

SRC: NLM .