Keppra XR Dosage
Generic name: Levetiracetam Extended-Release Tablets
Brand names: Keppra XR, Roweepra XR
Drug class: Pyrrolidine anticonvulsants
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: ER TAB: 500 mg, 750 mg
Partial seizures
- [1000-3000 mg PO qd]
- Start: 1000 mg PO qd, may incr. by 1000 mg/day q2wk; Max: 3000 mg/day; Info: dose adjustment may be needed during pregnancy and/or postpartum; do not cut/crush/chew tab; taper dose gradually to D/C
Renal dosing
- [adjust dose amount]
- CrCl 50-80: 1000-2000 mg qd; CrCl 30-50: 500-1500 mg qd; CrCl <30: 500-1000 mg qd
- HD/PD: not defined; Info: consider IR form
Hepatic dosing
- [no adjustment]
Recommended Peds Dosing
- Dosage forms: ER TAB: 500 mg, 750 mg
Partial seizures
- [12 yo and older]
- Dose: 1000-3000 mg PO qd; Start: 1000 mg PO qd, may incr. by 1000 mg/day q2wk; Max: 3000 mg/day; Info: do not cut/crush/chew tab; taper dose gradually to D/C
Renal dosing
- [adjust dose amount]
- CrCl 50-80: 1000-2000 mg qd; CrCl 30-50: 500-1500 mg qd; CrCl <30: 500-1000 mg qd
- HD/PD: not defined; Info: consider IR form
Hepatic dosing
- [no adjustment]
SRC: NLM .