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Lampit Dosage

Generic name: nifurtimox
Drug class: Miscellaneous antibiotics

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  TAB: 30 mg, 120 mg

Chagas dz

[8-10 mg/kg/day PO divided tid-qid x60-90 days]
Info: give w/ food

Human African trypanosomiasis

[15 mg/kg/day PO divided tid x10 days]
Info: for 2nd stage dz caused by Trypanosoma brucei gambiense; give w/ eflornithine; refer to CDC guidelines; give w/ food

Renal dosing

severe dz: avoid use
HD/PD: avoid use

Hepatic dosing

severe dz: avoid use

Recommended Peds Dosing

Dosage forms:  TAB: 30 mg, 120 mg

Chagas dz

[2.5-4.5 kg]
Dose: 15 mg PO tid x60-90 days; Info: give w/ food
[4.6-8.9 kg]
Dose: 30 mg PO tid x60-90 days; Info: give w/ food
[9-12.9 kg]
Dose: 45 mg PO tid x60-90 days; Info: give w/ food
[13-17.9 kg]
Dose: 60 mg PO tid x60-90 days; Info: give w/ food
[18-21.9 kg]
Dose: 75 mg PO tid x60-90 days; Info: give w/ food
[22-26.9 kg]
Dose: 90 mg PO tid x60-90 days; Info: give w/ food
[27-34.9 kg]
Dose: 120 mg PO tid x60-90 days; Info: give w/ food
[35-40.9 kg]
Dose: 180 mg PO tid x60-90 days; Info: give w/ food
[41-50.9 kg]
Dose: 120 mg PO tid x60-90 days; Info: give w/ food
[51-70.9 kg]
Dose: 180 mg PO tid x60-90 days; Info: give w/ food
[71-91 kg]
Dose: 240 mg PO tid x60-90 days; Info: give w/ food
[>91 kg]
Dose: 300 mg PO tid x60-90 days; Info: give w/ food

Human African trypanosomiasis

[15 mg/kg/day PO divided tid x10 days]
Info: for 2nd stage dz caused by Trypanosoma brucei gambiense; give w/ eflornithine; refer to CDC guidelines; give w/ food

Renal dosing

severe dz: avoid use
HD/PD: avoid use

Hepatic dosing

severe dz: avoid use

 

SRC: NLM .

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