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Levophed Dosage

Generic name: norepinephrine
Drug classes: Catecholamines, Vasopressors

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ

Hypotension, acute

[weight-based dosing]
Dose: 0.02-1 mcg/kg/min IV; Start: 0.1-0.5 mcg/kg/min IV, then titrate to effect; Info: pts w/ septic shock may require higher doses
[non weight-based dosing]
Dose: 2-4 mcg/min IV; Start: 8-12 mcg/min IV, then titrate to effect; Info: pts w/ septic shock may require higher doses

Cardiac arrest, adjunct tx

[weight-based dosing]
Dose: 0.02-1 mcg/kg/min IV; Start: 0.1-0.5 mcg/kg/min IV, then titrate to effect; Info: for post-resuscitation stabilization
[non weight-based dosing]
Dose: 2-4 mcg/min IV; Start: 8-12 mcg/min IV, then titrate to effect; Info: for post-resuscitation stabilization

Renal dosing

renal impairment: no adjustment
HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Hypotension, acute

[2-12 yo]
Dose: 0.1-2 mcg/kg/min IV; Start: 0.05-0.1 mcg/kg/min IV, then titrate to effect; Max: 2 mcg/kg/min

Post-resuscitation stabilization

[0.1-2 mcg/kg/min IV]
Start: 0.05-0.1 mcg/kg/min IV, then titrate to effect; Max: 2 mcg/kg/min; Info: refer to PALS guidelines

Renal dosing

[no adjustment]
renal impairment: no adjustment
HD/PD: no adjustment; no supplement

Hepatic dosing

[not defined]

 

SRC: NLM .

 

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