Olumiant Dosage

Generic name: baricitinib
Drug classes: Antirheumatics, Selective immunosuppressants

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 1 mg, 2 mg, 4 mg

Rheumatoid arthritis, mod-severe

[2 mg PO qd]

Info: use alone or w/ methotrexate or other non-biologic DMARDs; see pkg insert for toxicity-related dose adjustments

COVID-19

[4 mg PO qd]

Info: for hospitalized pts requiring supplemental oxygen, mechanical ventilation, or extracorporeal membrane oxygenation (ECMO); may give w/ remdesivir; cont. for 14 days or until hospital discharge, whichever comes first; see pkg insert for toxicity-related dose adjustments; search ‘COVID’ for additional resources including guidelines, published study summaries, and clinical trial updates

Alopecia areata, severe

[2-4 mg PO qd]

Info: may incr. dose to 4 mg PO qd if inadequate response or in pts w/ nearly complete or complete scalp hair loss; decr. dose to 2 mg PO qd after adequate response; see pkg insert for toxicity-related dose adjustments

Renal dosing

[rheumatoid arthritis]

eGFR 30-59: 1 mg qd; eGFR <30: avoid use

HD/PD: not defined

[COVID-19]

eGFR 30-59: 2 mg qd; eGFR 15-29: 1 mg qd; eGFR <15: avoid use

HD/PD: avoid use

[alopecia areata]

eGFR 30-59: decr. usual dose by 50%; eGFR <30: avoid use

HD/PD: not defined

Hepatic dosing

mild-moderate impairment: no adjustment; severe impairment: not defined

SRC: NLM .