Peramivir Dosage

Recommended Adult Dosing

Dosage forms:  INJ

Influenza A and B (seasonal flu) tx, uncomplicated

[600 mg IV x1]

Start: w/in 48h of sx onset

Renal dosing

[adjust dose amount]

CrCl 30-49: 200 mg x1; CrCl 10-29: 100 mg x1; CrCl <10: not defined

HD: 100 mg x1, on dialysis days admin. after dialysis; no supplement; PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Influenza A and B (seasonal flu) tx, uncomplicated

[6 mo-12 yo]

Dose: 12 mg/kg/dose IV x1; Start: w/in 48h of sx onset; Max: 600 mg/dose

[13 yo and older]

Dose: 600 mg IV x1; Start: w/in 48h of sx onset

Renal dosing

[6 mo-1 yo]

CrCl <50: not defined, caution advised

HD/PD: not defined, caution advised

[2-12 yo]

CrCl 30-49: 4 mg/kg/dose x1, max 600 mg/dose; CrCl 10-29: 2 mg/kg/dose x1, max 600 mg/dose; CrCl <10: not defined, caution advised

HD/PD: not defined, caution advised

[13 yo and older]

CrCl 30-49: 200 mg x1; CrCl 10-29: 100 mg x1; CrCl <10: not defined

HD: not defined, consider adult renal dosing for guidance; PD: not defined

Hepatic dosing

[not defined]