Qualaquin Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: CAP: 324 mg
Malaria, uncomplicated
- [2 caps PO q8h x3 days]
- Info: give w/ doxycycline, tetracycline, or clindamycin; if P. falciparum infection acquired in Southeast Asia, give x7 days; give w/ food; to avoid relapse in acute P. vivax or P. ovale infection, follow up tx w/ primaquine; refer to CDC guidelines
*Babesiosis
- [2 caps PO q6-8h x7-10 days]
- Info: give w/ clindamycin; not 1st-line regimen; tx for at least 6wk if immunocompromised; give w/ food
Renal dosing
- [malaria]
- mild-mod. renal impairment: not defined; severe chronic renal impairment: 2 caps x1, then 1 cap q12h
- HD: 2 caps q24h, on dialysis days admin. after dialysis; no supplement; PD: 2 caps q24h; no supplement
- [babesiosis]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class A or B: no adjustment, monitor closely; Child-Pugh Class C: avoid use
Recommended Peds Dosing
- Dosage forms: CAP: 324 mg
Malaria, uncomplicated
- [30 mg/kg/day PO divided q8h x3 days]
- Max: 2 caps/dose; Info: give w/ doxycycline, tetracycline, or clindamycin; if P. falciparum infection acquired in Southeast Asia, give x7 days; give w/ food; to avoid relapse in acute P. vivax or P. ovale infection, follow up tx w/ primaquine; refer to CDC guidelines
Babesiosis
- [8 mg/kg/dose PO q6-8h x7-10 days]
- Max: 2 caps/dose; Info: give w/ clindamycin; not 1st-line regimen; tx for at least 6wk if immunocompromised; give w/ food
Renal dosing
- [malaria]
- renal impairment: consider adult renal dosing for guidance
- HD/PD: consider adult renal dosing for guidance
- [babesiosis]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class A or B: no adjustment, monitor closely; Child-Pugh Class C: avoid use
SRC: NLM .