Bavencio Dosage

Generic name: avelumab
Drug class: Anti-PD-1 monoclonal antibodies

Medically reviewed by  A Ras MD.

Adult Dosing

Dosage forms:  INJ

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses, premeds, and dosing incl. toxicity-related dose adjustments

Merkel cell carcinoma, metastatic

[800 mg IV q2wk]

Urothelial carcinoma, locally advanced or metastatic

[maintenance tx]

Dose: 800 mg IV q2wk; Info: for pts w/ no disease progression after platinum-based first-line tx

[relapsed or refractory dz]

Dose: 800 mg IV q2wk; Info: for pts w/ disease progression during or w/in 12mo of platinum-based tx

Renal cell CA, advanced

[800 mg IV q2wk]

Info: use w/ axitinib

Renal dosing

CrCl >15: no adjustment; CrCl <15: not defined

HD/PD: not defined

Hepatic dosing

bilirubin 1-3x ULN or AST >ULN: no adjustment; bilirubin >3x ULN: not defined

SRC: NLM .