Benlysta Dosage
Generic name: belimumab
Drug class: Selective immunosuppressants
Medically reviewed by A Ras MD.
Adult Dosing
Dosage forms: INJ (auto-injector): 200 mg; INJ (pre-filled syringe): 200 mg per mL; INJ (vial): various
SLE
- [IV route]
- Dose: 10 mg/kg/dose IV q4wk; Start: 10 mg/kg/dose IV q2wk x3 doses
- [SC route]
- Dose: 200 mg SC qwk; Info: give 1st SC dose 1-4wk after last IV dose when switching to SC
Lupus nephritis
- [IV route]
- Dose: 10 mg/kg/dose IV q4wk; Start: 10 mg/kg/dose IV q2wk x3 doses; Info: may transition to SC route after at least 2 doses administered IV
- [SC route]
- Dose: 200 mg SC qwk; Start: 400 mg SC qwk x4 doses; Info: if transitioning from IV route, give 200 mg SC qwk 1-2wk after at least 2 doses administered IV
Renal dosing
- CrCl >15: no adjustment; CrCl <15: not defined
- HD/PD: not defined
Hepatic dosing
- [no adjustment]