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Bridion Dosage

Generic name: sugammadex
Drug class: Miscellaneous central nervous system agents

Medically reviewed by  A Ras MD.

 

Adult Dosing

Dosage forms:  INJ

Nondepolarizing neuromuscular blockade reversal

    [rocuronium or vecuronium moderate blockade]Dose: 2 mg/kg/dose IV x1; Info: for pts undergoing surgery w/ spontaneous recovery reaching reappearance of 2nd twitch to train-of-four; use ABW to calculate dose
    [rocuronium or vecuronium deep blockade]Dose: 4 mg/kg/dose IV x1; Info: for pts undergoing surgery w/ spontaneous twitch response recovery reaching 1-2 post-tetanic counts and no twitch response to train-of-four; use ABW to calculate dose
    [rocuronium immediate reversal]Dose: 16 mg/kg/dose IV x1; Info: for pts undergoing surgery requiring reversal after rocuronium 1.2 mg/kg/dose IV x1; use ABW to calculate dose

Renal dosing

CrCl <30: avoid use
HD/PD: avoid use

Hepatic dosing

[not defined]

 

SRC: NLM .

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