Brigatinib Dosage

Generic name: brigatinib
Brand name: Alunbrig
Dosage form: oral tablet (180 mg; 30 mg; 90 mg; 90 mg-180 mg)
Drug class: Multikinase inhibitors

Medically reviewed by  A Ras MD.

Adult Dosing

Dosage forms:  TAB: 30 mg, 90 mg, 180 mg

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

ALK-positive non-small cell lung CA, metastatic

[90 mg PO qd x7 days, then 180 mg PO qd]

Info: do not cut/crush/chew tab

Renal dosing

CrCl 15-29: decr. usual dose by approx. 50% as follows: if taking 180 mg, decr. to 90 mg; if taking 90 mg, decr. to 60 mg; CrCl <15: not defined

HD/PD: not defined

Hepatic dosing

Child-Pugh Class C: decr. usual dose by approx. 40% as follows: if taking 180 mg, decr. to 120 mg, if taking 120 mg, decr. to 90 mg; if taking 90 mg, decr. to 60 mg

SRC: NLM .