Celexa Dosage
Generic name: citalopram
Drug class: Selective serotonin reuptake inhibitors
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 10 mg, 20 mg, 40 mg
Major depressive disorder
- [20-40 mg PO qd]
- Start: 20 mg PO qd, may incr. to 40 mg PO qd after 1wk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers and pts >60 yo; taper dose gradually to D/C
Obsessive-compulsive disorder
- [40-60 mg PO qd]
- Start: 20 mg PO qd, incr. by 20 mg/day qwk; Max: 60 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers and pts >60 yo; taper dose gradually to D/C
Renal dosing
- [see below]
- mild-moderate impairment: no adjustment; severe impairment: not defined
- HD/PD: not defined
Hepatic dosing
- [adjust dose amount]
- hepatic impairment: max 20 mg/day
Recommended Peds Dosing
- Dosage forms: TAB: 10 mg, 20 mg, 40 mg
Major depressive disorder
[7-11 yo]
- Dose: 20-40 mg PO qd; Start: 10 mg PO qd, incr. by 5 mg/day q2wk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C
[12 yo and older]
- Dose: 20-40 mg PO qd; Start: 20 mg PO qd, may incr. by 10 mg/day q2wk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C
Generalized anxiety disorder
[7-17 yo]
- Dose: 10-40 mg PO qd; Start: 5-10 mg PO qd, may incr. dose q2-4wk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C
Obsessive-compulsive disorder
[7-12 yo]
- Dose: 10-60 mg PO qd; Start: 2.5-10 mg PO qd, may incr. by 5 mg/day q3wk; Max: 60 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C
[13 yo and older]
- Dose: 10-60 mg PO qd; Start: 10-20 mg PO qd, may increase. by 10 mg/day q3wk; Max: 60 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C
Intermittent explosive disorder
[7-17 yo]
- Dose: 10-40 mg PO qd; Start: 10 mg PO qd, may incr. by 10 mg/day qwk; Max: 40 mg/day; Info: max 20 mg/day in poor CYP2C19 metabolizers; taper dose gradually to D/C
Renal dosing
[not defined]
- renal impairment: consider adult renal dosing for guidance
- HD/PD: not defined
Hepatic dosing
[not defined]
- hepatic impairment: consider adult hepatic dosing for guidance
SRC: NLM .