Corifact Dosage
Generic name: factor XIII
Brand names: Corifact, Tretten
Drug class: Miscellaneous coagulation modifiers
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ
Congenital factor XIII deficiency
- [individualize dose IV q4wk]
- Start: 40 units/kg/dose IV x1; Info: for bleeding prophylaxis; estimate dose q4wk based on most recent trough factor XIII level w/ goal factor XIII trough level 5-20%; if factor XIII trough level <5% incr. dose 5 units/kg, if two factor XIII trough levels >20% or one factor XIII trough level >25% decr. dose 5 units/kg
Renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- [not defined]
Recommended Peds Dosing
- Dosage forms: INJ
Congenital factor XIII deficiency
- [individualize dose IV q4wk]
- Start: 40 units/kg/dose IV x1; Info: for bleeding prophylaxis; estimate dose q4wk based on most recent trough factor XIII level w/ goal factor XIII trough level 5-20%; if factor XIII trough level <5% incr. dose 5 units/kg, if two factor XIII trough levels >20% or one factor XIII trough level >25% decr. dose 5 units/kg
Renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- [not defined]
SRC: NLM .