Cystagon Dosage

Generic name: cysteamine
Brand names: Cystagon, Procysbi
Drug class: Miscellaneous uncategorized agents

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  CAP: 50 mg, 150 mg

Nephropathic cystinosis

[2000 mg/m^2/day PO divided q6h]

Start: 333-500 mg/m^2/day PO divided q6h, then increase dose over 4-6wk; Info: monitor WBC cystine level q3mo; adjust dose by 10% to maintain WBC cystine level <1 nmol ½ cys/mg protein; for pts <110 lb, consider start dose 215-325 mg/m^2/day PO divided q6h, then increase dose over 4-6wk to 1300 mg/m^2/day PO divided q6h up to 1950 mg/m^2/day

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

 Recommended Peds Dosing

Dosage forms:  CAP: 50 mg, 150 mg

Nephropathic cystinosis

[0-12 yo or <110 lb]

Dose: 1300 mg/m^2/day PO divided q6h; Start: 215-325 mg/m^2/day PO divided q6h, then increase dose over 4-6wk; Max: 1950 mg/m^2/day; Info: monitor WBC cystine level q3mo; adjust dose by 10% to maintain WBC cystine level <1 nmol ½ cys/mg protein

[>12 yo, >110 lb]

Dose: 2000 mg/m^2/day PO divided q6h; Start: 333-500 mg/m^2/day PO divided q6h, then increase dose over 4-6wk; Info: monitor WBC cystine level q3mo; adjust dose by 10% to maintain WBC cystine level <1 nmol ½ cys/mg protein

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .