Eloctate Dosage

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Hemophilia A

[bleeding episode, minor-moderate]

Dose: individualize dose IV q24-48h until hemostasis; Info: estimated dose (units) is [wt (kg) x desired factor VIII level (%) x 0.5] where desired factor VIII level 40-60%

[bleeding episode, major]

Dose: individualize dose IV q12-24h until hemostasis; Info: estimated dose (units) is [wt (kg) x desired factor VIII level (%) x 0.5] where desired factor VIII level 80-100%

[bleeding prophylaxis, minor surgery]

Dose: individualize dose IV x1 preop, then repeat dose IV q24h for at least 1 day until healing complete; Info: estimated dose (units) is [wt (kg) x desired factor VIII level (%) x 0.5] where desired factor VIII level 50-80%

[bleeding prophylaxis, major surgery]

Dose: 40-60 units/kg/dose IV x1 preop, then 40-50 units/kg/dose IV x1 8-24h postop, then repeat dose IV q24h for at least 7 days after healing complete; Info: desired factor VIII level 80-120%

[routine bleeding prophylaxis]

Dose: 25-65 units/kg/dose IV q3-5 days; Start: 50 units/kg/dose IV q4 days

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Hemophilia A

[bleeding episode, minor-moderate, 2-5 yo]

Dose: individualize dose IV q12-24h until hemostasis; Info: estimated dose (units) is [wt (kg) x desired factor VIII level (%) x 0.5] where desired factor VIII level 40-60%

[bleeding episode, minor-moderate, 6 yo and older]

Dose: individualize dose IV q24-48h until hemostasis; Info: estimated dose (units) is [wt (kg) x desired factor VIII level (%) x 0.5] where desired factor VIII level 40-60%

[bleeding episode, major, 2-5 yo]

Dose: individualize dose IV q8-24h until hemostasis; Info: estimated dose (units) is [wt (kg) x desired factor VIII level (%) x 0.5] where desired factor VIII level 80-100%

[bleeding episode, major, 6 yo and older]

Dose: individualize dose IV q12-24h until hemostasis; Info: estimated dose (units) is [wt (kg) x desired factor VIII level (%) x 0.5] where desired factor VIII level 80-100%

[bleeding prophylaxis, minor surgery, 2-5 yo]

Dose: individualize dose IV x1 preop, then repeat dose IV q12-24h for at least 1 day until healing complete; Info: estimated dose (units) is [wt (kg) x desired factor VIII level (%) x 0.5] where desired factor VIII level 50-80%

[bleeding prophylaxis, minor surgery, 6 yo and older]

Dose: individualize dose IV x1 preop, then repeat dose IV q24h for at least 1 day until healing complete; Info: estimated dose (units) is [wt (kg) x desired factor VIII level (%) x 0.5] where desired factor VIII level 50-80%

[bleeding prophylaxis, major surgery, 2-5 yo]

Dose: 40-60 units/kg/dose IV x1 preop, then 40-50 units/kg/dose IV x1 6-24h postop, then repeat dose IV q24h for at least 7 days after healing complete; Info: desired factor VIII level 80-120%

[bleeding prophylaxis, major surgery, 6 yo and older]

Dose: 40-60 units/kg/dose IV x1 preop, then 40-50 units/kg/dose IV x1 8-24h postop, then repeat dose IV q24h for at least 7 days after healing complete; Info: desired factor VIII level 80-120%

[routine bleeding prophylaxis]

Dose: 25-65 units/kg/dose IV q3-5 days; Start: 50 units/kg/dose IV q4 days; Info: more frequent or higher doses up to 80 units/kg/dose may be required for pts <6 yo

Renal dosing

[not defined]

renal impairment: not defined

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .