Exforge Dosage
Generic name: amlodipine and valsartan
Drug class: Angiotensin II inhibitors with calcium channel blockers
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 5 mg/160 mg, 5 mg/320 mg, 10 mg/160 mg, 10 mg/320 mg
HTN
- [initial tx]
- Dose: 1 tab PO qd; Start: 5 mg/160 mg PO qd, may incr. dose after 1-2wk; Max: 10 mg/320 mg/day; Info: avoid initial tx in elderly pts as lower amlodipine doses not possible w/ fixed-dose combo
- [replacement or add-on tx]
- Dose: 1 tab PO qd; Start: same dose of each component if replacement tx or start combo at lower dose of either component if add-on tx; may incr. dose after 3-4wk; Max: 10 mg/320 mg/day
Renal dosing
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
Hepatic dosing
- hepatic impairment: avoid use as initial tx; Info: lower amlodipine doses not possible w/ fixed-dose combo
SRC: NLM .