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Farydak Dosage

Generic name: panobinostat
Drug class: Histone deacetylase inhibitors

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  CAP: 10 mg, 15 mg, 20 mg

Multiple myeloma, progressive

[20 mg PO x1 on days 1, 3, 5, 8, 10, 12 of 21-day cycle]
Info: give up to 16 cycles; part of multi-drug chemo regimen; do not open cap

Renal dosing

renal impairment: no adjustment; ESRD: not defined
HD/PD: not defined

Hepatic dosing

bilirubin 1-1.5x ULN or AST >ULN: 15 mg; bilirubin 1.5-3x ULN and any AST: 10 mg; bilirubin >3x ULN: avoid use

 

SRC: NLM .

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