Fentora Dosage
Generic name: fentanyl (buccal/sublingual)
Brand names: Abstral, Fentora, Subsys
Drug class: Narcotic analgesics
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: BUC TAB: 100 mcg, 200 mcg, 400 mcg, 600 mcg, 800 mcg
Restricted Distribution in US
Special Note
- [prescribing info]
- Info: consider prescribing naloxone if risk of opioid overdose or accidental ingestion
- [formulation clarification]
- Info: transmucosal fentanyl products not bioequivalent, caution advised if switching between products; see pkg insert for conversion from other transmucosal forms; not interchangeable w/ other fentanyl products, do not substitute on a mcg to mcg basis
Breakthrough cancer pain, opioid-tolerant pts
- [individualize dose buccally/SL x1 prn]
- Start: 100 mcg buccally x1, may repeat x1 after 30min; Max: 4 tabs/dose; 2 doses/episode; Info: use lowest effective dose, shortest effective tx duration; must wait at least 4h before treating another episode; for initial titration incr. dose by 100 mcg/episode prn; titrate by 200 mcg if dose >400 mcg; for maint. dosing, consider incr. dose after several consecutive episodes require 2 doses; may give maint. doses SL; do not cut/chew/swallow tab; taper dose gradually to D/C if no longer require opioid tx
Renal dosing
- renal impairment: not defined, caution advised
- HD/PD: not defined
Hepatic dosing
- [not defined]
- hepatic impairment: caution advised
SRC: NLM .