Gamifant Dosage
Generic name: emapalumab
Drug class: Selective immunosuppressants
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ
Primary hemophagocytic lymphohistiocytosis
- [1-10 mg/kg/dose IV q3-4 days]
- Start: 1 mg/kg/dose IV q3-4 days, adjust dose based on response (see pkg insert); Info: for refractory, recurrent, progressive dz or intolerance w/ conventional tx; use w/ dexamethasone 5-10 mg/m^2/day
Renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
Hepatic dosing
- [no adjustment]
Recommended Peds Dosing
- Dosage forms: INJ
Primary hemophagocytic lymphohistiocytosis
- [1-10 mg/kg/dose IV q3-4 days]
- Start: 1 mg/kg/dose IV q3-4 days, adjust dose based on response (see pkg insert); Info: for refractory, recurrent, progressive dz or intolerance w/ conventional tx; use w/ dexamethasone 5-10 mg/m^2/day
Renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
Hepatic dosing
- [no adjustment]
SRC: NLM .