Glucarpidase Dosage

Generic name: glucarpidase
Brand name: Voraxaze
Drug class: Antidotes

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ

Methotrexate toxicity

[50 units/kg/dose IV x1]

Info: for pts w/ methotrexate concentration >2 standard deviations above expected mean methotrexate excretion curve

Renal dosing

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ

Methotrexate toxicity

[50 units/kg/dose IV x1]

Info: for pts w/ methotrexate concentration >2 standard deviations above expected mean methotrexate excretion curve

Renal dosing

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .