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Humalog Dosage

Generic name: insulin lispro
Drug class: Insulin

Medically reviewed by  A Ras MD.

 

Recommended Adult Dosing

Dosage forms:  INJ (U-100 cartridge): 100 units per mL; INJ (KwikPen U-100 pen, Junior KwikPen U-100 pen, Tempo U-100 pen): 100 units per mL; INJ (U-100 vial): 100 units per mL; INJ (KwikPen U-200 pen): 200 units per mL

Diabetes mellitus

[intermittent SC injection]
Dose: individualize dose SC bid-qid; Info: usual total daily insulin requirement 0.5-1 units/kg/day (basal + prandial); give <15min before or immediately after meals; dose adjustment may be needed during pregnancy and/or immed. postpartum; onset <0.5h, peak 0.5-1.5h, duration <6h (rapid-acting insulin)
[continuous SC infusion]
Dose: individualize dose (100 units/mL) via continuous SC infusion pump; Info: usual total daily insulin requirement 0.5-1 units/kg/day (basal + prandial); dose adjustment may be needed during pregnancy and/or immed. postpartum; onset <0.5h, peak 0.5-1.5h, duration <6h (rapid-acting insulin)
[IV route]
Dose: individualize dose (100 units/mL) IV infusion; Info: refer to institutional protocol; dose adjustment may be needed during pregnancy and/or immed. postpartum

Renal dosing

renal impairment: consider decr. usual dose
HD/PD: consider decr. usual dose; no supplement

Hepatic dosing

[adjust dose amount]
hepatic impairment: decr. dose, amount not defined

Recommended Peds Dosing

Dosage forms:  INJ (U-100 cartridge): 100 units per mL; INJ (Junior KwikPen U-100 pen, KwikPen U-100 pen, Tempo U-100 pen): 100 units per mL; INJ (U-100 vial): 100 units per mL; INJ (KwikPen U-200 pen): 200 units per mL

Diabetes mellitus, type 1

[intermittent SC injection, 3 yo and older]
Dose: individualize dose SC bid-qid; Info: usual total daily insulin requirement 0.5-1 units/kg/day (basal + prandial); adolescents may require higher doses; give <15min before or immediately after meals; onset <0.5h, peak 0.5-1.5h, duration <6h (rapid-acting insulin)
[continuous SC infusion, 3 yo and older]
Dose: individualize dose (100 units/mL) via continuous SC infusion pump; Info: usual total daily insulin requirement 0.5-1 units/kg/day (basal + prandial); adolescents may require higher doses; onset <0.5h, peak 0.5-1.5h, duration <6h (rapid-acting insulin)

Diabetes mellitus, type 2

[intermittent SC injection]
Dose: individualize dose SC bid-qid; Info: usual total daily insulin requirement 0.5-1 units/kg/day (basal + prandial); adolescents may require higher doses; give <15min before or immediately after meals; onset <0.5h, peak 0.5-1.5h, duration <6h (rapid-acting insulin)
[continuous SC infusion]
Dose: individualize dose (100 units/mL) via continuous SC infusion pump; Info: usual total daily insulin requirement 0.5-1 units/kg/day (basal + prandial); adolescents may require higher doses; onset <0.5h, peak 0.5-1.5h, duration <6h (rapid-acting insulin)

Renal dosing

renal impairment: consider decr. usual dose
HD/PD: consider decr. usual dose; no supplement

Hepatic dosing

[adjust dose amount]
hepatic impairment: decr. dose, amount not defined

SRC: NLM .

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