Imfinzi Dosage

Generic name: durvalumab
Drug class: Anti-PD-1 monoclonal antibodies

Medically reviewed by A Ras MD

Recommended Adult Dosing

Dosage forms: INJ

[1-844-275-2360 or www.imfinzi.com for more info]

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

[10 mg/kg/dose IV q2wk for up to 12mo]

Alt: 1500 mg IV q4wk for up to 12mo if wt >30 kg; Info: for non-progressive dz after concurrent platinum-based chemo and XRT

[>30 kg]

Dose: 1500 mg IV q3wk; Info: part of multi-drug chemo regimen for 1st 4 cycles

[<30 kg]

Dose: 20 mg/kg/dose IV q3wk x4 cycles, then 10 mg/kg/dose IV q2wk; Info: part of multi-drug chemo regimen for 1st 4 cycles

[indication withdrawn in US]

Info: drug not shown to improve survival in pts w/ locally advanced or metastatic urothelial carcinoma

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

bilirubin 1.1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN and any AST: not defined

SRC: NLM .