Kineret Dosage

Generic name: anakinra
Drug classes: Antirheumatics, Interleukin inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ (pre-filled syringe): 100 mg per 0.67 mL

Rheumatoid arthritis, mod-severe

[100 mg SC q24h]

Info: for monotherapy or in combination w/ other anti-rheumatics except TNF blocking agents

Neonatal-onset multisystem inflammatory dz

[3-4 mg/kg/dose SC q24h]

Start: 1-2 mg/kg/dose SC q24h, may incr. by 0.5-1 mg/kg/day; Max: 8 mg/kg/day; Info: may divide dose bid

Interleukin-1 receptor antagonist deficiency

[1-8 mg/kg/dose SC q24h]

Start: 1-2 mg/kg/dose SC q24h, may incr. by 0.5-1 mg/kg/day; Max: 8 mg/kg/dose

Renal dosing

CrCl <30: give usual dose q48h

HD/PD: not defined

Hepatic dosing

[not defined]

Recommended Peds Dosing

Dosage forms:  INJ (pre-filled syringe): 100 mg per 0.67 mL

Neonatal-onset multisystem inflammatory dz

[3-4 mg/kg/dose SC q24h]

Start: 1-2 mg/kg/dose SC q24h, may incr. by 0.5-1 mg/kg/day; Max: 8 mg/kg/day; Info: may divide dose bid

Interleukin-1 receptor antagonist deficiency

[1-8 mg/kg/dose SC q24h]

Start: 1-2 mg/kg/dose SC q24h, may incr. by 0.5-1 mg/kg/day; Max: 8 mg/kg/dose

Renal dosing

CrCl <30: give usual dose q48h

HD/PD: not defined

Hepatic dosing

[not defined]

SRC: NLM .