Lanreotide Dosage
Generic name: lanreotide
Brand name: Somatuline Depot
Drug class: Somatostatin and somatostatin analogs
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ (pre-filled syringe): 60 mg per 0.2 mL, 90 mg per 0.3 mL, 120 mg per 0.5 mL
Acromegaly
- [60-120 mg SC q4wk]
- Start: 90 mg SC q4wk x3mo; Info: adjust dose based on GH and IGF-1 levels; may give 120 mg SC q6wk or q8wk if controlled on 60 mg or 90 mg SC q4wk
Gastroenteropancreatic neuroendocrine tumor, advanced
- [120 mg SC q4wk]
Carcinoid syndrome
- [120 mg SC q4wk]
Renal dosing
- [acromegaly]
- CrCl <60: start 60 mg q4wk; Info: caution advised if considering 120 mg q6wk or q8wk
- HD/PD: not defined
- [gastroenteropancreatic neuroendocrine tumor, advanced]
- CrCl >30: no adjustment; CrCl <30: not defined
- HD/PD: not defined
- [carcinoid syndrome]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- [acromegaly]
- Child-Pugh Class B or C: start 60 mg q4wk; Info: caution advised if considering 120 mg q6wk or q8wk
- [all other indications]
- hepatic impairment: not defined
SRC: NLM .