Makena Dosage

Generic name: hydroxyprogesterone injection
Drug class: Progestins

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  INJ (auto-injector): 275 mg; INJ (vial): 250 mg per mL

Premature birth risk reduction

[auto-injector form]

Dose: 275 mg SC qwk until 37 wk gestation or delivery; Start: between 16 wk 0 day gestation and 20 wk 6 days gestation

[vial form]

Dose: 250 mg IM qwk until 37 wk gestation or delivery; Start: between 16 wk 0 day gestation and 20 wk 6 days gestation

Renal dosing

renal impairment: not defined, caution advised

HD/PD: not defined, caution advised

Hepatic dosing

[not defined]

hepatic impairment: caution advised

SRC: NLM .