Mepron Dosage
Generic name: atovaquone
Drug class: Miscellaneous antibiotics
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: SUSP: 750 mg per 5 mL
PCP prophylaxis
- [1500 mg PO qd]
- Info: not 1st-line agent; give w/ food
PCP tx, mild-mod.
- [750 mg PO bid x21 days]
- Info: not 1st-line agent; give w/ food
Toxoplasmosis prophylaxis, primary
- [1500 mg PO qd]
- Info: not 1st-line agent; give w/ food
Toxoplasmosis prophylaxis, secondary
- [750-1500 mg PO q12h]
- Info: not 1st-line agent; give w/ food
Toxoplasmosis tx
- [1500 mg PO q12h for at least 6wk]
- Info: not 1st-line agent; give w/ food
Babesiosis
- [750 mg PO q12h x7-10 days]
- Info: give w/ azithromycin as 1st-line regimen; tx for at least 6wk if immunocompromised; give w/ food
Renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- [not defined]
- severe impairment: caution advised
Recommended Peds Dosing
- Dosage forms: SUSP: 750 mg per 5 mL
PCP prophylaxis
- [1-3 mo]
- Dose: 30 mg/kg/dose PO qd; Max: 1500 mg/day; Info: not 1st-line agent; give w/ food
- [4-24 mo]
- Dose: 45 mg/kg/dose PO qd; Max: 1500 mg/day; Info: not 1st-line agent; give w/ food
- [2-12 yo]
- Dose: 30 mg/kg/dose PO qd; Max: 1500 mg/day; Info: not 1st-line agent; give w/ food
- [13 yo and older]
- Dose: 1500 mg PO qd; Info: not 1st-line agent; give w/ food
PCP tx, mild-mod.
- [<3 mo]
- Dose: 30-40 mg/kg/day PO divided q12h x21 days; Max: 1500 mg/day; Info: not 1st-line agent; give w/ food
- [3-24 mo]
- Dose: 45 mg/kg/day PO divided q12h x21 days; Max: 1500 mg/day; Info: not 1st-line agent; give w/ food
- [2-12 yo]
- Dose: 30-40 mg/kg/day PO divided q12h x21 days; Max: 1500 mg/day; Info: not 1st-line agent; give w/ food
- [13 yo and older]
- Dose: 750 mg PO bid x21 days; Info: not 1st-line agent; give w/ food
Toxoplasmosis prophylaxis, primary
- [1-3 mo]
- Dose: 30 mg/kg/dose PO qd; Info: not 1st-line agent; give w/ food
- [4-24 mo]
- Dose: 45 mg/kg/dose PO qd; Info: not 1st-line agent; give w/ food
- [2-12 yo]
- Dose: 30 mg/kg/dose PO qd; Info: not 1st-line agent; give w/ food
- [13 yo and older]
- Dose: 1500 mg PO qd; Info: not 1st-line agent; give w/ food
Toxoplasmosis prophylaxis, secondary
- [1-3 mo]
- Dose: 30 mg/kg/dose PO qd; Info: not 1st-line agent; give w/ food
- [4-24 mo]
- Dose: 45 mg/kg/dose PO qd; Info: not 1st-line agent; give w/ food
- [2-12 yo]
- Dose: 30 mg/kg/dose PO qd; Info: not 1st-line agent; give w/ food
- [13 yo and older]
- Dose: 750-1500 mg PO q12h; Info: not 1st-line agent; give w/ food
Toxoplasmosis tx
- [13 yo and older]
- Dose: 1500 mg PO q12h for at least 6wk; Info: not 1st-line agent; give w/ food
Babesiosis
- [20 mg/kg/dose PO q12h x7-10 days]
- Max: 750 mg/dose; Info: give w/ azithromycin as 1st-line regimen; tx for at least 6wk if immunocompromised; give w/ food
Renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- [not defined]
- severe impairment: caution advised
SRC: NLM .