Micafungin Dosage
Generic name: micafungin
Brand name: Mycamine
Dosage form: intravenous powder for injection (100 mg; 50 mg)
Drug class: Echinocandins
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ
Candidemia
- [100 mg IV q24h]
Candidiasis, acute disseminated
- [100 mg IV q24h]
Candidal peritonitis and abscesses
- [100 mg IV q24h]
Candidiasis, esophageal
- [150 mg IV q24h]
Candidiasis prophylaxis, stem cell transplant
- [50 mg IV q24h]
*Candidiasis, oropharyngeal
- [100 mg IV q24h]
- Info: for fluconazole-refractory dz
*Endocarditis, candidal
- [150 mg IV q24h]
- Info: for native valve endocarditis; not 1st-line agent; refer to IDSA and AHA guidelines
*Febrile neutropenia
- [100-150 mg IV q24h]
- Info: for empiric tx in high-risk pts w/ persistent fever
Renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
Hepatic dosing
- [no adjustment]
Recommended Peds Dosing
- Dosage forms: INJ
Candidemia
- [<4 mo]
- Dose: 4 mg/kg/dose IV q24h; Info: for pts w/o meningoencephalitis and/or ocular dissemination
- [4 mo and older]
- Dose: 2 mg/kg/dose IV q24h; Max: 100 mg/day
Candidiasis, acute disseminated
- [<4 mo]
- Dose: 4 mg/kg/dose IV q24h; Info: for pts w/o meningoencephalitis and/or ocular dissemination
- [4 mo and older]
- Dose: 2 mg/kg/dose IV q24h; Max: 100 mg/day
Candidal peritonitis and abscesses
- [<4 mo]
- Dose: 4 mg/kg/dose IV q24h; Info: for pts w/o meningoencephalitis and/or ocular dissemination
- [4 mo and older]
- Dose: 2 mg/kg/dose IV q24h; Max: 100 mg/day
Candidiasis, esophageal
- [4 mo and older, <31 kg]
- Dose: 3 mg/kg/dose IV q24h
- [4 mo and older, >31 kg]
- Dose: 2.5 mg/kg/dose IV q24h; Max: 150 mg/day
Candidiasis prophylaxis, stem cell transplant
- [4 mo and older]
- Dose: 1 mg/kg/dose IV q24h; Max: 50 mg/day
Renal dosing
- [no adjustment]
- renal impairment: no adjustment
- HD/PD: no adjustment; no supplement
Hepatic dosing
- [no adjustment]
SRC: NLM .