Nexavar Dosage

Generic name: sorafenib
Drug classes: Multikinase inhibitors, VEGF/VEGFR inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  TAB: 200 mg

Hepatocellular CA, unresectable

[400 mg PO bid]

Info: give at least 1h before or 2h after food

Renal cell CA, advanced

[400 mg PO bid]

Info: give at least 1h before or 2h after food

Differentiated thyroid CA, refractory

[400 mg PO bid]

Info: for pts w/ locally recurrent or metastatic, progressive dz and who are radioactive iodine-refractory; give at least 1h before or 2h after food

Renal dosing

renal impairment: no adjustment

HD/PD: not defined

Hepatic dosing

Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: not defined

SRC: NLM .