Ofev Dosage

Generic name: nintedanib
Drug class: Multikinase inhibitors

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  CAP: 100 mg, 150 mg

Idiopathic pulmonary fibrosis

[150 mg PO q12h]

Max: 300 mg/day; Info: see pkg insert for dose adjustments based on toxicities; give w/ food; do not open cap

Chronic fibrosing interstitial lung dz

[150 mg PO q12h]

Max: 300 mg/day; Info: for pts w/ progressive phenotype; see pkg insert for dose adjustments based on toxicities; give w/ food; do not open cap

Systemic sclerosis-assoc. interstitial lung dz

[150 mg PO q12h]

Max: 300 mg/day; Info: see pkg insert for dose adjustments based on toxicities; give w/ food; do not open cap

Renal dosing

CrCl >30: no adjustment; CrCl <30: not defined

HD/PD: not defined

Hepatic dosing

Child-Pugh Class A: 100 mg q12h; Child-Pugh Class B or C: avoid use

SRC: NLM .