Onureg Dosage
Generic name: azacitidine
Drug class: Miscellaneous antineoplastics
Recommended Adult Dosing
Dosage forms: TAB: 200 mg, 300 mg
AML
- [300 mg PO qd on days 1-14 of 28-day cycle]
- Info: for continued tx in pts who achieved complete remission (CR) or CR w/ incomplete hematologic recovery (CRi) after intensive induction chemo, and ineligible for intensive curative tx; do not cut/crush/chew tab
Renal dosing
- CrCl >30: no adjustment; CrCl <30: not defined, caution advised
- HD/PD: not defined
Hepatic dosing
- bilirubin 1-1.5x ULN or AST >ULN: no adjustment; bilirubin >1.5x ULN and any AST: not defined
SRC: NLM .