Pegvisomant Dosage
Generic name: pegvisomant
Brand name: Somavert
Drug class: Growth hormone receptor blockers
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: INJ: 10 mg per mL, 15 mg per mL, 20 mg per mL, 25 mg per mL, 30 mg per mL
Restricted Distribution in US
Acromegaly
- [10-30 mg SC qd]
- Start: 40 mg SC x1 on day 1, then 10 mg SC qd; Max: 30 mg/day; Info: may adjust dose by 5 mg/day q4-6wk based on IGF-1 levels
Renal dosing
- [not defined]
- renal impairment: not defined
- HD/PD: not defined
Hepatic dosing
- [no adjustment]
- baseline LFTs >3x ULN: weigh risk/benefit
SRC: NLM .