Pomalyst Dosage

Generic name: pomalidomide
Drug classes: Miscellaneous antineoplastics, Other immunosuppressants

Medically reviewed by  A Ras MD.

Recommended Adult Dosing

Dosage forms:  CAP: 1 mg, 2 mg, 3 mg, 4 mg

Restricted Distribution in US

Special Note

[uses, dosing may vary]

Info: refer to institution protocols and pkg insert prior to prescribing for uses and dosing incl. toxicity-related dose adjustments

Multiple myeloma, relapsed or refractory

[4 mg PO qd on days 1-21 of 28-day cycle]

Info: for pts who have received at least 2 prior tx, incl. lenalidomide and a proteasome inhibitor, and w/ dz progression on or w/in 60 days after last tx; use w/ dexamethasone +/- elotuzumab, daratumumab, daratumumab/hyaluronidase, or isatuximab; do not open cap

Kaposi sarcoma

[5 mg PO qd on days 1-21 of 28-day cycle]

Info: for pts w/ HIV-negative dz or AIDS-related dz after HAART failure; do not open cap

Renal dosing

[multiple myeloma]

renal impairment: not defined

HD: 3 mg PO qd, on dialysis days admin. after dialysis; no supplement; PD: not defined

[Kaposi sarcoma]

renal impairment: not defined

HD: 4 mg PO qd, on dialysis days admin. after dialysis; no supplement; PD: not defined

Hepatic dosing

[multiple myeloma]

Child-Pugh Class A or B: 3 mg PO qd; Child-Pugh Class C: 2 mg PO qd

[Kaposi sarcoma]

Child-Pugh Class A, B or C: 3 mg PO qd

SRC: NLM .