Prevymis Dosage
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 240 mg, 480 mg; INJ: various
CMV prophylaxis, allogeneic HSCT
- [480 mg PO/IV qd until 100 days post-transplant]
- Start: between days 0 and 28 of transplant; Info: for CMV seropositive recipients; switch to PO form when possible
Renal dosing
- [PO route]
- CrCl >10: no adjustment; CrCl <10: not defined
- HD/PD: not defined
- [IV route]
- CrCl >50: no adjustment; CrCl <50: not defined, caution advised; Info: PO route preferred due to accumulation of toxic IV vehicle
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class A or B: no adjustment; Child-Pugh Class C: avoid use
SRC: NLM .