RediTrex Dosage

Generic name: methotrexate (injection route, subcutaneous route)

Medically reviewed by  A Ras MD.

 Recommended Adult Dosing

Dosage forms:  INJ (pre-filled syringe): 7.5 mg per 0.3 mL, 10 mg per 0.4 mL, 12.5 mg per 0.5 mL, 15 mg per 0.6 mL, 17.5 mg per 0.7 mL, 20 mg per 0.8 mL, 22.5 mg per 0.9 mL, 25 mg per mL

Rheumatoid arthritis

[7.5-25 mg SC qwk]

Start: 7.5 mg SC qwk; Max: 30 mg/wk; Info: use lowest effective dose; give w/ folic acid 1 mg qd or leucovorin 5 mg qwk; consider lower doses in elderly pts

 Psoriasis, severe

[10-25 mg SC qwk]

Max: 30 mg/wk; Info: use lowest effective dose; give w/ folic acid 1 mg qd or leucovorin 5 mg qwk; consider lower doses in elderly pts

Renal dosing

CrCl 10-50: decr. usual dose by 50%; CrCl <10: avoid use

HD: decr. usual dose by 50%, on dialysis days admin. after dialysis; no supplement; PD: avoid use

Hepatic dosing

chronic hepatic dz: contraindicated

SRC: NLM .