Safinamide Dosage
Generic name: safinamide
Brand name: Xadago
Drug class: Dopaminergic antiparkinsonism agents
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 50 mg, 100 mg
Parkinson dz, adjunct tx
- [50-100 mg PO qd]
- Start: 50 mg PO qd x2wk, then may incr. to 100 mg PO qd; Max: 100 mg/day; Info: use w/ carbidopa/levodopa; decr. dose to 50 mg/day x1wk to D/C
Renal dosing
- [see below]
- renal impairment: no adjustment
- HD/PD: not defined
Hepatic dosing
- Child-Pugh Class B: max 50 mg/day; Child-Pugh Class C: contraindicated
SRC: NLM .