Savella Dosage
Generic name: milnacipran hydrochloride
Medically reviewed by A Ras MD.
Recommended Adult Dosing
Dosage forms: TAB: 12.5 mg, 25 mg, 50 mg, 100 mg; convenience pack
Fibromyalgia
- [50 mg PO bid]
- Start: 12.5 mg PO qd x1 day, then 12.5 mg PO bid x2 days, then 25 mg PO bid x4 days, then 50 mg PO bid; Max: 200 mg/day; Info: taper dose gradually to D/C
Renal dosing
- CrCl > 60: no adjustment; CrCl 30-59: not defined, caution advised; CrCl 5-29: decr. usual dose by 50%, max 100 mg/day; ESRD: avoid use
- HD/PD: not defined
Hepatic dosing
- severe impairment: caution advised; chronic hepatic dz: avoid use
SRC: NLM .