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Succimer

Generic name: succimer
Brand name: Chemet
Dosage form: oral capsule (100 mg)
Drug class: Chelating agents

Medically reviewed by  A Ras MD.

What is succimer used for?

Succimer is a prescription medicine that is used to treat lead poisoning.

Description

Succimer is an orally active, heavy metal chelating agent. The chemical name for succimer is meso 2, 3-dimercaptosuccinic acid (DMSA). Its empirical formula is C 4642 and molecular weight is 182.2. The meso-structural formula is:

Succimer

Succimer is a white crystalline powder with an unpleasant, characteristic mercaptan odor and taste.

Each CHEMET opaque white capsule for oral administration contains beads coated with 100 mg of succimer and is imprinted black with CHEMET 100. Inactive ingredients in medicated beads are: povidone, sodium starch glycolate, starch and sucrose. Inactive ingredients in capsule are: gelatin, iron oxide, titanium dioxide and other ingredients.

Before taking succimer, tell your doctor:

  • If you are allergic to succimer; any part of this medicine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
  • If you are using another drug like this one. If you are not sure, ask your doctor or pharmacist.
  • If you are breast-feeding. Do not breast-feed while you take succimer.

This is not a list of all drugs or health problems that interact with succimer.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take succimer with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take succimer?

  • Tell all of your health care providers that you take succimer. This includes your doctors, nurses, pharmacists, and dentists.
  • Have blood work checked as you have been told by the doctor. Talk with the doctor.
  • This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take succimer.
  • You will need to be sure that you are not dehydrated before getting succimer. Check with your doctor to see if you need to drink extra fluids before getting succimer.
  • Do not take succimer for longer than you were told by your doctor.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using succimer while you are pregnant.

How is succimer best taken?

Use succimer as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • You may sprinkle contents of capsule on soft food. Contents may also be put in a spoon and followed with fruit drink.
  • Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.

What do I do if I miss a dose?

  • Take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.

What are the side effects of succimer that I need to call my doctor about immediately?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Signs of infection like fever, chills, very bad sore throat, ear or sinus pain, cough, more sputum or change in color of sputum, pain with passing urine, mouth sores, or wound that will not heal.
  • A burning, numbness, or tingling feeling that is not normal.
  • Rectal irritation.
  • Ear pain.

What are some other side effects of succimer?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Upset stomach or throwing up.
  • Metallic taste.
  • Diarrhea.
  • Not hungry.
  • Feeling sleepy.
  • Dizziness.
  • Lower back or side pain.
  • Stomach cramps.
  • Belly pain.
  • Headache.
  • Flu-like signs.
  • Feeling tired or weak.
  • Signs of a common cold.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

If overdose is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out succimer?

  • Store at room temperature.
  • Protect from heat.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

SRC: NLM .

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